Trinity’s position as one of the world’s leading universities is defined by our research, scholarship, and capacity to address issues of global, societal and economic importance. Our strength lies in the breadth and excellence of our expertise; from individual-scholars and thought-leaders, to large multidisciplinary teams, each delivering research of national and global importance.
Trinity Biomedical Sciences Institute is an environment where innovative and interdisciplinary approaches are leading to scientific discoveries of biomedical importance, ultimately giving rise to better patient care. The mechanistic basis for a whole range of diseases is under investigation including infectious and inflammatory diseases such as arthritis and Type 2 diabetes, neurological diseases such as motor neurone disease and multiple sclerosis, and different forms of cancer.
Our focus is on outstanding discovery, since there remains a major unmet medical need for the treatment of these diseases and our understanding of the molecular basis of many diseases remains limited.
Our focus has always been on the core discipline of biochemistry and how it helps us understand organic life and the fundamental mechanisms that underlie human disease. In more recent years we have expanded our biochemistry teaching and research activities into the area of Immunology which has generated an internationally renowned reputation. Our school is a collegial and dynamic community of researchers and our mission is to create a rich educational experience for our undergraduates, graduate students and postdoctoral researchers. While our School is research intensive it maintains a strong international reputation for the quality of its scholarly activities.
There are currently 25 research groups in our school and areas of research in Biochemistry include membrane proteins, enzymology, folic acid biochemistry, structural biology, tRNA biology, neurochemistry, neurodegeneration, metabolism, systems biology, cancer biology, molecular parasitology, apoptosis and drug discovery
The Trinity College Institute of Neuroscience (TCIN) is a Trinity Research Institute (TRI) with 50 Principal Investigators and 250 researchers from a wide range of disciplines including Psychology, Psychiatry, Physiology, Pharmacology, Medicine, Biochemistry, Engineering, and Genetics, among others. These diverse disciplinary origins contribute to its core activities: promoting and supporting interdisciplinary basic and translational research, as well as teaching, public engagement, and national leadership in Neuroscience.
The Institute provides a gateway for internal and external connectivity between basic and applied Neuroscience. TCIN facilitates access to advanced research and diagnostic technologies as well as to patient populations, biosamples, and genotyping required for translational Neuroscience, which prominently and deeply involves clinical PIs based in St James, St Patrick’s and Tallaght Hospitals. St James additionally houses CAMI, a clinical Neuroimaging facility as well as the Wellcome-Trust HRB Clinical Research Facility for clinical trials.
The Florey Institute of Neuroscience and Mental Health is the largest brain research group in the Southern Hemisphere. Our teams work on a range of serious diseases including stroke, epilepsy, Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, Huntington’s disease, motor neurone disease, traumatic brain and spinal cord injury, depression, schizophrenia, mental illness and addiction. We are world leaders in imaging technology, stroke rehabilitation and epidemiological studies.
Research of the brain and its diseases has gained considerable momentum internationally. Many scientific and technological advancements have been made, and much of our work has been centre stage. Our scientific home is a hive of activity with researchers coming from around the globe to work at the Florey. State and Federal Governments, major philanthropic foundations and many generous private benefactors have recognised the importance of neuroscience as the final frontier in medical research.